Smoother Skin with Relfydess: A New Innovation in Aesthetic Medicine

The field of aesthetics is constantly evolving, and 2025 marks the arrival of a significant advancement. A next-generation botulinum toxin, Relfydess, is set to launch in the UK, offering a new approach to wrinkle treatments. Unlike traditional botulinum toxins, this innovative formulation is designed to provide rapid results, an extended duration of effect, and a more convenient treatment experience. At Riverbanks Clinic, we are always committed to offering cutting-edge options, and we are excited to explore how our patients could benefit from smoother skin with Relfydess.

How Is Relfydess Different?

One of the key differences with Relfydess is that it comes as a ready-to-use liquid formulation. Unlike other botulinum toxins that require reconstitution before administration, Relfydess eliminates this additional step. This means that every dose is delivered with precision and consistency, ensuring predictable results. Consequently, patients can expect a more refined appearance and smoother skin with Relfydess treatment.

When Can You Expect to See Results?

With Relfydess, results may appear significantly faster than with traditional botulinum toxins. Clinical studies have indicated that up to 39% of patients saw a reduction in frown lines within 24 hours, while 34% of patients noticed improvements in crow’s feet within the same timeframe.

Typically, other neuromodulators require between three to five days before visible effects begin to show. In contrast, the faster onset of Relfydess makes it a convenient option for those seeking prompt results, whether in preparation for a special event or simply to maintain a youthful, refreshed look.

Does Relfydess Last Longer?

Not only does Relfydess offer a faster onset, but it has also been designed to deliver longer-lasting results. While most traditional botulinum toxins begin to wear off after three to four months, clinical studies suggest that Relfydess may maintain its effects for up to six months.

In fact, by the six-month mark, approximately 75% of patients still reported smoother skin with Relfydess. This extended duration means that fewer maintenance treatments may be required, allowing for a lower-maintenance approach to wrinkle care.

What About Safety?

Relfydess has undergone extensive clinical evaluation to ensure both its safety and efficacy. In clinical trials, less than 20% of patients experienced mild side effects, such as temporary redness or swelling at the injection site. Importantly, these reactions resolved quickly and did not affect patient satisfaction.

Furthermore, even with repeated treatments over a 12-month period, no new safety concerns were identified. Patients reported high levels of satisfaction with both the results and the treatment experience. As with any aesthetic procedure, it is essential to consult a qualified medical professional to determine whether this treatment is suitable for you.

Want to Learn More about Smoother Skin with Relfydess?

If you are interested in exploring whether Relfydess could be right for you, we invite you to book a complimentary consultation at Riverbanks Clinic. Our expert team will be happy to provide guidance on the best aesthetic solutions tailored to your needs.

📞 Call us on 01582 762877
📅 Book online at riverbanksclinic.co.uk/book

Let’s work together to create your smoothest, most youthful look yet!

References

1. READY-1 Trial: Shridharani SM, et al. “Efficacy and Safety of RelabotulinumtoxinA, a New Ready-to-Use Liquid Formulation Botulinum Toxin: Results From the READY-1 Double-Blind, Randomized, Placebo-Controlled Phase 3 Trial in Glabellar Lines.” Aesthetic Surgery Journal, 2024; sjae131. https://pubmed.ncbi.nlm.nih.gov/38913088/
2. READY-2 Trial: Ablon G, et al. “Treatment of Lateral Canthal Lines with RelabotulinumtoxinA, an Investigational Liquid Botulinum Toxin: Clinical Efficacy and Safety Results from the READY-2 Phase III Trial.” Abstract presented at TOXINS 2024; Jan 17-20, 2024, Berlin. https://www.galderma.com/news/results-galdermas-phase-iiib-trials-demonstrate-rapid-and-long-lasting-effect-0
3. READY-3 Trial: Bertucci V, et al. “Efficacy and Safety of a Novel Formulation Liquid Botulinum Toxin, RelabotulinumtoxinA, when used for Combination Treatment of Glabellar and Lateral Canthal Lines.” Abstract presented at TOXINS 2024; Jan 17-20, 2024, Berlin. https://www.galderma.com/news/results-galdermas-phase-iiib-trials-demonstrate-rapid-and-long-lasting-effect-0
4. READY-4 Trial: Beer K, et al. “READY-4: Long-term safety with repeated injections using RelabotulinumtoxinA, a novel liquid formulation botulinum toxin, in the treatment of glabellar and lateral canthal lines.” E-poster presented at: ASDS 2024; October 17-20, 2024; Orlando, FL. https://www.galderma.com/news/asds-2024-new-phase-iii-ready-4-data-demonstrate-long-term-safety-and-efficacy-galdermas
5. RELAX Trial: Galderma. “IMCAS 2025: New Galderma phase IIIb data reinforce rapid onset and long-lasting aesthetic efficacy of RelabotulinumtoxinA (Relfydess).” January 31, 2025. https://www.galderma.com/news/imcas-2025-new-galderma-phase-iiib-data-reinforce-rapid-onset-and-long-lasting-aesthetic

Relfydess Training for Medical Professionals

If you’re looking to future-proof your injectable practice, consider joining our Relfydess training programme. Designed for licensed medical professionals, these hands-on workshops cover everything from reconstitution to advanced injection techniques using relabotulinumtoxinA. With a maximum of 5 delegates per session, you’ll benefit from personalised teaching, training product on the day, and optional access to models. Hosted at the award-winning Riverbanks Wellness Clinic—just 10 minutes from Luton Airport—these sessions are led by Dr Ravi Jain, a key UK trainer and early adopter of Relfydess.